Human Milk Oligosaccharides


Most human milk oligosaccharides are fucosylated oligosaccharides, which is not the case for the oligosaccharides produced by dairy animals. The most abundant oligosaccharide in human milk is 2′-Fucosyllactose, with a concentration of about 2 grams per liter.

Because 2′-Fucosyllactose is present at relatively high concentrations in human milk, it was possible to isolate and investigate this compound many years ago. Its specific functional benefits include its ability to reduce the risk of infection by widespread bacterial diarrheal pathogens, e.g. Campylobacter jejuni, pathogenic Escherichia coli, certain Salmonella species and the pneumonia-causing pathogen Pseudomonas aeruginosa. In cooperation with the University Children’s Hospital Mannheim of Heidelberg University, Jennewein Biotechnologie has confirmed the functional equivalence of our products 2′-Fucosyllactose and 3-Fucosyllactose. Further preclinical studies suggest that 2′-Fucosyllactose also has positive effects on the nervous system and cognition, as well as reducing the risk of inflammation such as in the case of necrotizing enterocolitis, for example.

Jennewein Biotechnologie produces 2′-Fucosyllactose on a commercial scale. The product is available as a spray-dried powder as well as a liquid concentrate. Our 2′-Fucosyllactose production facility is Kosher as well as Halal certified. Jennewein Biotechnologie and its local partners are happy to provide more detailed information about our product 2’‑Fucosyllactose on request.